Microfluidics for label-free particle sorting



Publications by fellows in the project



Beech, J. P., B. D. Ho, G. Garriss, V. Oliveira, B. Henriques-Normark and J. O. Tegenfeldt (2018). "Separation of pathogenic bacteria by chain length." Analytica Chimica Acta 1000: 223-231. Link to publication


Honrado, C., L. Ciuffreda, D. Spencer, L. Ranford-Cartwright and H. Morgan (2018). "Dielectric characterization of Plasmodium falciparum-infected red blood cells using microfluidic impedance cytometry." Journal of the Royal Society Interface 15(147). Link to full text


McGrath, J. S., C. Honrado, D. Spencer, B. Horton, H. L. Bridle and H. Morgan (2017). "Analysis of Parasitic Protozoa at the Single-cell Level using Microfluidic Impedance Cytometry." Scientific Reports 7. Link to full text


Tran, T. S. H., B. D. Ho, J. P. Beech and J. O. Tegenfeldt (2017). "Open channel deterministic lateral displacement for particle and cell sorting." Lab on a Chip 17(21): 3592-3600. Link to publication


Urbansky, A., P. Ohlsson, A. Lenshof, F. Garofalo, S. Scheding and T. Laurell (2017). "Rapid and effective enrichment of mononuclear cells from blood using acoustophoresis." Scientific Reports 7. Link to full text


Xavier, M., M. C. de Andres, D. Spencer, R. O. C. Oreffo and H. Morgan (2017). "Size and dielectric properties of skeletal stem cells change critically after enrichment and expansion from human bone marrow: consequences for microfluidic cell sorting." Journal of the Royal Society Interface 14(133). Link to full text


Ewan Henry, Stefan H. Holm, Zunmin Zhang, Jason P. Beech, Jonas O. Tegenfeldt, Dmitry A. Fedosov & Gerhard Gompper: Sorting cells by their dynamical properties. Scientific Reports 6, Article number: 34375 (2016) doi:10.1038/srep34375
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Federico Iovino, Disa L. Hammarlöf, Genevieve Garriss, Sarah Brovall, Priyanka Nannapaneni, and Birgitta Henriques-Normark: Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA. J Clin Invest. 2016;126(8):2821-2826. doi:10.1172/JCI84705.
Link to full text


Anke Urbansky, Andreas Lenshof, Josefina Dykes, Thomas Laurell and Stefan Scheding: Affinity-Bead-Mediated Enrichment of CD8+ Lymphocytes from Peripheral Blood Progenitor Cell Products Using Acoustophoresis. Micromachines 2016, 7(6), 101; doi:10.3390/mi7060101
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Miguel Xavier, ROC Oreffo and H. Morgan: Skeletal stem cell isolation: A review on the state-of-the-art microfluidic label-free sorting techniques. Biotechnology Advances, 2016, 34(5), 908–923.
Link to abstract


Lisa Ranford-Cartwright and Laura Ciuffreda (2016): Molecular approaches for diagnosis of malaria and characterization of genetic markers for drug resistance. p 516-529. In: Persing D, Tenover F, Hayden R, Ieven M, Miller M, Nolte F, Tang Y, van Belkum A (ed), Molecular Microbiology. ASM Press, Washington, DC. doi: 10.1128/9781555819071.ch37


Xavier, M., P. Rosendahl, M. Herbig, M. Krater, D. Spencer, M. Bornhauser, R. O. C. Oreffo, H. Morgan, J. Guck and O. Otto: Mechanical phenotyping of primary human skeletal stem cells in heterogeneous populations by real-time deformability cytometry. Integrative Biology (2016). Open access available at DOI: 10.1039/C5IB00304K


Houssin, T., J. Cramer, R. Grojsman, L. Bellahsene, G. Colas, H. Moulet, W. Minnella, C. Pannetier, M. Leberre, A. Plecis and Y. Chen: Ultrafast, sensitive and large-volume on-chip real-time PCR for the molecular diagnosis of bacterial and viral infections. Lab on a Chip (2016) 16 (8): 1401-1411. DOI: 10.1039/C5LC01459J See abstract at the Journal's site


Zunmin Zhang, Ewan Henry, Gerhard Gompper and Dmitry A. Fedosov: Behavior of rigid and deformable particles in deterministic lateral displacement devices with different post shapes, J. Chem. Phys. 143, 243145 (2015); See fulltext at the Journal's site


Lenshof A, Jamal A, Dykes J, Urbansky A, Åstrand-Grundström I, Laurell T and Scheding S.: Efficient purification of CD4+ lymphocytes from peripheral blood progenitor cell products using affinity bead acoustophoresis. Cytometry, Part A. 2014. 85(11):933-41. Link to abstract




Scientific Posters


Acoustic separation of mixed particle suspensions using an improved microfluidic-based multiple outlet chip.
Authors: A. Urbansky, T. Laurell, A. Lenshof. Presented at the Micronano System Workshop (MSW 2016), in Lund from the 17th-18th May, 2016.


Label-free Characterization and Sorting of Human Pathogens.
Authors: C. Honrado, J. McGrath, L. Ciuffreda, D. Spencer, H. Bridle, L. Ranford-Cartwright and H. Morgan. Presented at Zepler Institute Nano Research Group Seminar held at the University of Southampton in May 2015.

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Skeletal stem cell sorting: characterisation of bio-physical properties for microfluidic separation applications
Authors: M. Xavier, P. Rosendahl, D. Spencer, O .Otto, J. Guck, R. O. C. Oreffo and H. Morgan.
Presented at the Tissue and Cell Engineering Society (TCES 2015) Conference held at the Grand Harbour Hotel from the 19th-21th July, 2015.
The abstract was published as a supplement in European Cells and Materials Vol. 29. Suppl. 3, 2015 (page 109) and is downloadable through the Journal's site.

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A Lab on a Chip to Isolate Human Skeletal Stem Cells for Bone Regeneration
Authors: M. Xavier, P. Rosendahl, D. Spencer, O .Otto, J. Guck, R. O. C. Oreffo and H. Morgan. Presented at the CHB Lab Visit of Her Royal Highness the Duchess of Cornwall, in Southampton on the 11th February, 2016.

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Label-free sorting of P. falciparum-infected cells to improve the diagnosis of human malaria.
Authors: Ciuffreda L., Honrado C., Punyani K., Otto O., Herold C. , Morgan H. , Tegenfeldt J., Guck J. , Ranford-Cartwright L.

Presented at the conference "Glasgow Encounters with Tropical Disease" held at the University of Glasgow on 8th January 2016.

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Separation of parasites and parasite-infected cells from blood for the diagnosis of leishmaniasis.
Authors: Regnault C., Honrado C., Punyani K., Otto O., Herold C., Morgan H., Tegenfeldt J., Guck J., Barrett MP.

Presented at the conference "Glasgow Encounters with Tropical Disease" held at the University of Glasgow on 8th January 2016.

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© Stefan Holm 2014; last updated January 2019 by GRE